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Inflammatory myofibroblastic tumor in the larynx: clinicopathologic features and histogenesis.
- Source :
-
Acta Oto-Laryngologica . Feb2005, Vol. 125 Issue 2, p215-219. 5p. - Publication Year :
- 2005
-
Abstract
- Inflammatory myofibroblastic tumor is extremely rare in the larynx and can mimic a malignant process. We present the case of a 62-year-old male who required tracheotomy due to rapidly progressive stridor. Laryngoscopy showed an exophytic, occlusive tumor located in the right true vocal cord. CT showed an expansive mass measuring 2×2×1.3 cm 3 and occupying the anterior commissure, with glottic progression to the right true vocal cord. The tumor was completely resected with a CO 2 laser via a transoral approach. Histologic examination demonstrated extensive ulceration with the presence of granulation tissue. The specimen was mainly composed of spindle cells arranged in a fasciculated pattern with a myxoid background and focal hyalinization. Immunohistochemical studies revealed positivity of spindle cells to vimentin, muscle-specific actin and smooth muscle actin. The patient showed no evidence of disease 24 months after surgery. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TRACHEOTOMY
*TRACHEAL diseases
*OTOLARYNGOLOGY
LARYNGEAL tumors
Subjects
Details
- Language :
- English
- ISSN :
- 00016489
- Volume :
- 125
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Acta Oto-Laryngologica
- Publication Type :
- Academic Journal
- Accession number :
- 16009801
- Full Text :
- https://doi.org/10.1080/00016480410022796