Electrogram‐based AF ablation: finally, reproducibility!

The author reflects updates on the use of electrogram-based ablation and systematic pulmonary vein isolation (PVI) for substrate modification in persistent atrial fibrillation (AF). Other topics include the detection of complex fractionated atrial electrograms (CFAE), the concept of atrial substrate identification developed by J. Seitz and colleagues using spatiotemporal dispersion mapping, and the study on the use of reproducibility and advanced electrogram analysis technology.