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To evaluate the efficacy of thrombolytic treatment with IV streptokinase in individuals with acute ST elevation myocardial infarction.

Authors :
Chaturvedi, Neeraj
Agarwal, Ashish Kumar
Jalan, Shilpa
Source :
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research). 2022, Vol. 13 Issue 7, p560-565. 6p.
Publication Year :
2022

Abstract

Aim:The aim of the present study to evaluate the efficacy of thrombolytic treatment with IV streptokinase in individuals with acute ST elevation myocardial infarction. Methods: A prospective observational study was conducted in the Department of Cardiology. In all, 105 patients with acute ST segment elevation were analysed both before and after Streptokinase thrombolysis. The study population was separated into three groups based on the values they had. CategoryA:<30% resolution of the sum of Stsegment elevation. CategoryB:30%-70% resolution of the sum of ST segment elevation. CategoryC:>70% resolution of the sum of STsegmentelevation. Results: Male patients were substantially more prevalent (76.19%) than female patients (23.81%). In this investigation, the most prevalent mode of presentation was chest discomfort, which was present in 96(91.43%) patients and was accompanied with sweating in 87(82.86%) patients and dyspnea in 26(24.76%) patients. Palpitation was seen in 7(6.67%) individuals and syncope in 12(11.43%). In this research, anterior wall myocardial infarction did not differ from inferior wall myocardial infarction. The ratio of anterior wall MI (57.14%) to inferior wall MI (42.86%) is quite high. Complete ST resolution was seen in 40 (38.09%) instances, partial resolution in 49 (46.67%) cases, and no resolution in 16 (15.24%) cases. Conclusions: Patients with no ST segment resolution at 90 minutes post-thrombolysis were associated with more frequent adverse events and increased mortality compared to the partial and complete resolution group, leading us to conclude that IV streptokinase for thrombolysis in acute STEMI has an efficacy of 42.86 percent. The percentage of ST segment improvement after 90 minutes of thrombolysis is a useful diagnostic tool for determining patient risk. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09753583
Volume :
13
Issue :
7
Database :
Academic Search Index
Journal :
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research)
Publication Type :
Academic Journal
Accession number :
160194858