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Astrocyte dysfunction drives abnormal resting-state functional connectivity in depression.
- Source :
-
Science Advances . 11/18/2022, Vol. 8 Issue 46, p1-17. 17p. - Publication Year :
- 2022
-
Abstract
- The article presents a study which showed that the astrocytic calcium-deficient mice, inositol 1,4,5-trisphosphate-type-2 receptor knockout mice (Itpr2-/- mice), display abnormal resting-state functional magnetic resonance imaging (rsfMRI) functional connectivity (rsFC) in depression-related networks. Topics include characteristically consistent rsFC changes in major depressive disorder (MDD) patients and Itpr2-/- mice and data acquisition of resting-state fMRI and optogenetic fMRI experiments.
Details
- Language :
- English
- ISSN :
- 23752548
- Volume :
- 8
- Issue :
- 46
- Database :
- Academic Search Index
- Journal :
- Science Advances
- Publication Type :
- Academic Journal
- Accession number :
- 160299857
- Full Text :
- https://doi.org/10.1126/sciadv.abo2098