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The Evaluation of Relationship between Monocyte/High-Density Lipoprotein Ratio (MHR) and COVID-19.
- Source :
-
Konuralp Medical Journal / Konuralp Tip Dergisi . haz2022, Vol. 14 Issue 2, p386-390. 5p. - Publication Year :
- 2022
-
Abstract
- Objective: Early diagnosis is important for severe diseases in COVID-19. Monocyte/high density lipoprotein ratio (MHR) is a new prognostic marker indicating inflammation. We aimed to investigate the relationship between MHR and diseases severity in COVID-19. Methods: Patients with laboratory confirmed COVID-19, were retrospectively analyzed. Clinical symptoms, signs and laboratory data on the first day of hospitalization were obtained from medical records of hospital. The clinical data of 301 patients were included in study. Cases were diagnosed on the basis of interim guidance of World Health Organization (WHO). Patients were classified into two groups as non-severe COVID-19 and severe COVID-19. MHR were calculated with laboratory data on the first day of hospitalization. The relationship between MHR level and COVID-19 severity was evaluated. Statistical analysis of the data was performed by using SPSS 25 (SPSS Inc., Chicago, IL, USA) package program. Statistical significance level was accepted as p<0.05. Results: One hundred ninety-six patients (65.1 %) had non-severe COVID-19,105 patients (34.9 %) had severe COVID-19. In our study, it was found that the mean age was higher in severe patients and comorbid diseases were more common. Although monocyte count values were not statistically significantly different, MHR was significantly higher in severe COVID-19 than non-severe COVID-19. Conclusions: Monocytes are very important to cytokine storm in COVID-19. Dyslipidemia can occur in viral infection because of inflammation. MHR can be used as an inflammatory marker in COVID-19. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BIOMARKERS
*LENGTH of stay in hospitals
*HDL cholesterol
*GLOMERULAR filtration rate
*TROPONIN
*C-reactive protein
*ALBUMINS
*TRIGLYCERIDES
*PROTHROMBIN time
*COVID-19
*HEMOGLOBINS
*INFLAMMATION
*RETROSPECTIVE studies
*ACQUISITION of data
*FISHER exact test
*CALCITONIN
*SEVERITY of illness index
*CYTOKINE release syndrome
*HYPERLIPIDEMIA
*ARTIFICIAL respiration
*NEUTROPHIL lymphocyte ratio
*MEDICAL records
*DESCRIPTIVE statistics
*CHI-squared test
*FIBRINOGEN
*HIGH density lipoproteins
*DATA analysis software
*BLOOD cell count
*INTERNATIONAL normalized ratio
*MONOCYTES
*COMORBIDITY
*ALANINE aminotransferase
*ASPARTATE aminotransferase
*CREATININE
*CHOLESTEROL
Subjects
Details
- Language :
- English
- ISSN :
- 13093878
- Volume :
- 14
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Konuralp Medical Journal / Konuralp Tip Dergisi
- Publication Type :
- Academic Journal
- Accession number :
- 160312314
- Full Text :
- https://doi.org/10.18521/ktd.1099432