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Risk factors for seroconversion of HIV among children exposed in the State of Santa Catarina, 2007-2017.
- Source :
-
Brazilian Journal of Mother & Child Health (BJMCH) / Revista Brasileira de Saude Materno Infantil (RBSMI) . jul-set2022, Vol. 22 Issue 3, p577-592. 16p. - Publication Year :
- 2022
-
Abstract
- Objectives: to estimate the proportion of seroconversion cases among infants exposed to HIV and verify the risk factors associated. Methods: this was a historical cohort study conducted in the State of Santa Catarina between 2007 and 2017. The data were obtained from the Notifiable Diseases Information System (SINAN - Portuguese acronym) that records HIV-infected pregnant women and HIV-exposed infants. The public health service monitored the infants from birth to 18 months of age to determine whether HIV seroconversion occurred. Results: a total of 5,554 HIV-infected pregnant women were included in the study (mean age 26.7±6.5 years). They were predominantly white, with poor education level, and were diagnosed with HIV until the 2nd trimester of pregnancy. A total of 4,559 records of HIV-exposed infants were screened, of which 130 cases (2.9%) of seroconversion were confirmed. Non-use of antiretroviral drugs during pregnancy (OR=9.31, CI95%=5.97-14.52; p<0.001) and breastfeeding (OR=3.10, CI95%=1.34-7.20; p=0.008) were independent risk factors for seroconversion. Conclusions: these data demonstrate gaps in prenatal care, regarding adherence to treatment and monitoring of HIV-infected mothers, resulting in new cases of HIV among children, which could be avoided. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Multiple languages
- ISSN :
- 15193829
- Volume :
- 22
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Brazilian Journal of Mother & Child Health (BJMCH) / Revista Brasileira de Saude Materno Infantil (RBSMI)
- Publication Type :
- Academic Journal
- Accession number :
- 160702724
- Full Text :
- https://doi.org/10.1590/1806-9304202200030008