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Bcl11b and Atoh8 Coordinate Cellular Plasticity for Reprogramming and Transformation.

Authors :
Huang, Mo-Fan
Shoemaker, Rachel
Lee, Dung-Fang
Source :
Cellular Reprogramming. Dec2022, Vol. 24 Issue 6, p324-326. 3p.
Publication Year :
2022

Abstract

By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*TRANSCRIPTION factors

Details

Language :
English
ISSN :
21524971
Volume :
24
Issue :
6
Database :
Academic Search Index
Journal :
Cellular Reprogramming
Publication Type :
Academic Journal
Accession number :
160760211
Full Text :
https://doi.org/10.1089/cell.2022.0128