Progress in research on the reproductive function in the sand rat (Psammomys obesus): A review.

The Fat Sand Rat (Psammomys obesus, P. obesus) is a diurnal herbivore and phytophage, with seasonal reproductive behavior. The sexually active phase lasts from autumn to early spring and the sexually inactive phase from late spring to summer. In the past years, P. obesus has gained much attention as an animal model in biological and clinical research. It is a suitable model for diet-induced insulin resistance, non-insulin-dependent diabetes mellitus and obesity studies. In addition, the seasonal reproduction of P. obesus is gaining more and more attention. The current paper aims to review and sum up the progress in the understanding of the reproductive anatomo-histo-physiology of Psammomys obesus , in order to facilitate future research in this area and to expose further perspectives for researchers. • Psammomys obesus is a valuable animal model for biological and clinical research. • It is a suitable model for diet-induced insulin resistance, non-insulin-dependent diabetes mellitus and obesity studies. • The reproductive behavior of P. obesus corresponds to an ecophysiological adaptation. • P. obesus represents a suitable model for studying the mechanism of environmental restricted reproduction. [ABSTRACT FROM AUTHOR]