Preventing age‐related vascular dysfunction: the gut of the matter.

Keywords: ageing; trimethylamine N-oxide; vascular dysfunction EN ageing trimethylamine N-oxide vascular dysfunction 5181 5183 3 12/19/22 20221215 NES 221215 Cardiovascular disease (CVD) is the leading cause of death in the ageing population. Translational studies have shown that plasma concentrations of TMAO increase with age, and that TMAO directly contributes to age-related endothelial dysfunction and arterial stiffness by oxidative stress-mediated mechanisms (Fig. Preventing age-related vascular dysfunction: the gut of the matter. [Extracted from the article]