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[4+2]-Cycloaddition of 1,1,3,3-tetramethylguanidine and o-quinone methides: synthesis of arene-fused 2-dimethylamino-4H-1,3-oxazines.
- Source :
-
Russian Chemical Bulletin . Nov2022, Vol. 71 Issue 11, p2451-2459. 9p. - Publication Year :
- 2022
-
Abstract
- A method for producing substituted 4H-1,3-benzoxazines and their fused derivatives bearing N,N-dimethylamino moiety in the position 2 of 4H-1,3-oxazine ring from phenolic and naphtholic Mannich bases, their iodomethylates or salicylic alcohols, and 1,1,3,3-tetramethylguanidine has been developed. This reaction is supposed to proceed via the generation of o-quinone methides followed by [4+2]-cycloaddition and elimination of dimethylamine. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MANNICH bases
*DIMETHYLAMINE
*QUINONE
*MOIETIES (Chemistry)
*OXAZINES
Subjects
Details
- Language :
- English
- ISSN :
- 10665285
- Volume :
- 71
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Russian Chemical Bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 160868260
- Full Text :
- https://doi.org/10.1007/s11172-022-3673-1