Model-based prioritization for acquiring protection.

Protection often involves the capacity to prospectively plan the actions needed to mitigate harm. The computational architecture of decisions involving protection remains unclear, as well as whether these decisions differ from other beneficial prospective actions such as reward acquisition. Here we compare protection acquisition to reward acquisition and punishment avoidance to examine overlapping and distinct features across the three action types. Protection acquisition is positively valenced similar to reward. For both protection and reward, the more the actor gains, the more benefit. However, reward and protection occur in different contexts, with protection existing in aversive contexts. Punishment avoidance also occurs in aversive contexts, but differs from protection because punishment is negatively valenced and motivates avoidance. Across three independent studies (Total N = 600) we applied computational modeling to examine model-based reinforcement learning for protection, reward, and punishment in humans. Decisions motivated by acquiring protection evoked a higher degree of model-based control than acquiring reward or avoiding punishment, with no significant differences in learning rate. The context-valence asymmetry characteristic of protection increased deployment of flexible decision strategies, suggesting model-based control depends on the context in which outcomes are encountered as well as the valence of the outcome. Author summary: Acquiring protection is a ubiquitous way humans achieve safety. Humans make future-oriented decisions to acquire safety when they anticipate the possibility of future danger. These prospective safety decisions likely engage model-based control systems, which facilitate goal-oriented decision making by creating a mental map of the external environment. Inability to effectively use model-based control may reveal new insights into how safety decisions go awry in psychopathology. However, computational decision frameworks that can identify contributions of model-based control have yet to be applied to safety. Clinical science instead dominates and investigates decisions to seek out safety as a maladaptive response to threat. Focusing on maladaptive safety prevents a full understanding of how humans make decisions motivated by adaptive goals. The current studies apply computational models of decision control systems to understand how humans make adaptive decisions to acquire protection compared with acquiring reward and avoiding threat. Safety-motivated decisions elicited increased model-based control compared to reward- or threat-motivated decisions. These findings demonstrate that safety is not simply reward seeking or threat avoidance in a different form, but instead safety elicits distinct contributions of decision control systems important for goal-directed behavior. [ABSTRACT FROM AUTHOR]