Ozone Gas by Direct Injections Heals Chronic Anal Fissure — Case Report.

Ozone therapy delivered by local injections, together with topically applied ozonated vegetable oil, to a woman with chronic, extremely painful, and swollen anal fissure provided rapid relief of symptoms. All symptoms were abated by 14 sessions. Full healing occurred, which to date has endured over 2 years. Ozone by injection may be a superior form of delivery of this healing gas than rectal insufflation for anal fissure. The treatment is inexpensive, relatively non-invasive, and can be performed without pain under local anesthesia. [ABSTRACT FROM AUTHOR]