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Maternal infection with COVID-19 and increased risk of adverse pregnancy outcomes: a meta-analysis.
- Source :
-
Journal of Maternal-Fetal & Neonatal Medicine . Dec2022, Vol. 35 Issue 25, p9368-9375. 8p. - Publication Year :
- 2022
-
Abstract
- Background: The Coronavirus disease 2019 (COVID-19) pandemic has become worldwide, posing particularly severe challenges. Pregnancy brings changes that might make individuals more vulnerable to this viral infection. To date, the impact of COVID-19 infection on pregnancy outcomes remains controversial. Method: We performed a meta-analysis to address the impact of COVID-19 infection on pregnancy outcomes. We searched the PubMed and China National Knowledge infrastructure (CNKI) databases for related articles. The odds ratio (OR) corresponding to the 95% confidence interval (95% CI) was used to define the impact of INFECTION and severity of COVID-19 on pregnancy outcomes. The statistical heterogeneity among studies was batched with the Q-test and I² statistics. Results: We collected 38 studies including 127,805 pregnancy women. Our meta-analysis revealed that pregnant women with COVID-19 have been linked to an increased risk of premature birth (OR = 1.66, 95% CI = 1.41–1.96), stillbirth (OR = 1.98, 95% CI = 1.22–3.21), preeclampsia (OR = 1.46, 95% CI = 1.18–1.80), and PROM (OR = 1.39, 95% CI = 1.07–1.81). Conclusions: Our meta-analysis showed that infection with COVID-19 increases the risk of preterm birth, stillbirth, pre-eclampsia, and PROM. Screening and early care for pregnant women to intervene with COVID-19 is important, given the increased risk of adverse pregnancy outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PREGNANCY outcomes
*COVID-19
*COVID-19 pandemic
*PREGNANT women
*VIRUS diseases
Subjects
Details
- Language :
- English
- ISSN :
- 14767058
- Volume :
- 35
- Issue :
- 25
- Database :
- Academic Search Index
- Journal :
- Journal of Maternal-Fetal & Neonatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 161126444
- Full Text :
- https://doi.org/10.1080/14767058.2022.2033722