MRI‐informed cortical features for brain age prediction in age‐specific adulthoods.

For example, after fitting the age-bias correction coefficients from the training set, a child with a predicted brain age of 10 years gets an age bias-corrected brain age of 4 years, and an elderly with a predicted brain age of 80 years gets an age-bias corrected brain age of 94 years (Figure 1). Taken together, as we look toward future research focused on brain age prediction, a healthy control group with same mean age and age range as the targeted clinical groups is necessary to generate the age-bias correction coefficients when applying the BrainAGE as an aging biomarker in clinical populations. MRI-informed cortical features for brain age prediction in age-specific adulthoods. [Extracted from the article]