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Acid-catalyzed synthesis of 2,3-dihydronaphtho[2,3-b]furan and 3,4-dihydro-2H-benzo[g]chromene derivatives.
- Source :
-
Synthetic Communications . 2023, Vol. 53 Issue 1, p49-57. 9p. 6 Charts. - Publication Year :
- 2023
-
Abstract
- An efficient and facile method for producing 2,3-dihydronaphtho[2,3-b]furan and 3,4-dihydro-2H-benzo[g]chromene has been developed. This methodology utilizes an inexpensive and simple PTSA catalyst for the cyclization reaction of ortho-oxalate-, ortho-keto-, and ortho-formyl arylacetylenols to produce the corresponding products in high yield. This procedure was also successfully applied to the large-scale synthesis of the naphthofuran skeleton, which can be found in various natural products and pharmaceuticals. [ABSTRACT FROM AUTHOR]
- Subjects :
- *FURAN derivatives
*NATURAL products
*RING formation (Chemistry)
*SKELETON
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 53
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 161364853
- Full Text :
- https://doi.org/10.1080/00397911.2022.2149343