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Bacterial Meningitis among Intracranial Surgery Patients at a University Hospital in Northern India.
- Source :
-
Indian Journal of Critical Care Medicine . Dec2022, Vol. 26 Issue 12, p1244-1252. 9p. 4 Charts, 1 Graph. - Publication Year :
- 2022
-
Abstract
- Background: Cerebrospinal infections are the cause of poor prognosis among post-neurosurgery patients owing to delay in improvement of neurological functions, leading to increased length of hospital stay, proceeding to disability or death. Methods and materials: This retrospective observational study was performed at a tertiary care center in Northern India, where all patients with bacterial cerebrospinal infections from July 2019 to July 2022 were evaluated for post-neurosurgery cerebrospinal shunt infections, and all demographic data and risk factors were extracted from the hospital information system (HIS). Results: The study includes 150 (150/1986, 7.55%) culture-confirmed cases of bacterial meningitis out of 1986 cases of suspected bacterial meningitis patients. Ninety-six (96/150, 64.0%) post-neurosurgery patients with cerebrospinal fluid (CSF) leaks were managed using external ventricular drain (EVD) or ventriculo-peritoneal (VP) shunt. Seventy-four (74/96, 77.08%) patients were managed only on EVD, whereas 22 (22/96, 22.92%) patients were managed only on VP shunt. Eighty-two (82/96, 85.4%) multidrug-resistant microorganisms (MDROs)were isolated and 70 (70/82, 85.36%) were Gram-negative bacteria, of which 56 (56/74, 75.68%) Gram-negative bacteria showed extended-spectrum betalactamase (ESBL)-producing character in those with an EVD, 14 (14/22, 63.63%) with a VP shunt. Among Gram-negative bacteria, Acinetobacter baumannii showed high rates of resistance: 21 (21/23, 91.30%) and 8 (8/8, 100%) were ESBL-producing A. baumannii in patients managed on EVD and VP shunt, respectively. Conclusion: This study determines the risk factors, the spectrum of pathogenic microorganisms, multidrug resistance, and the nature of intracranial lesions isolated among the patients who developed bacterial cerebrospinal infections in post-neurosurgery patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BACTERIAL disease risk factors
*CEREBROSPINAL fluid leak
*ACADEMIC medical centers
*SCIENTIFIC observation
*NEUROSURGERY
*GRAM-negative bacteria
*SURGICAL complications
*SURGERY
*PATIENTS
*RETROSPECTIVE studies
*TERTIARY care
*BACTERIAL meningitis
*RISK assessment
*CEREBROSPINAL fluid shunts
*INFECTION
*DESCRIPTIVE statistics
*MULTIDRUG resistance
*CEREBROSPINAL fluid
*COMPLICATIONS of prosthesis
*COMORBIDITY
*DISEASE risk factors
CENTRAL nervous system infections
Subjects
Details
- Language :
- English
- ISSN :
- 09725229
- Volume :
- 26
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Critical Care Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 161370356