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Factors influencing sensitivity of a rapid influenza diagnostic test in a community‐based population of kindergarten through 12th‐grade students: Wisconsin 2015–2020.
- Source :
-
Influenza & Other Respiratory Viruses . Jan2023, Vol. 17 Issue 1, p1-6. 6p. - Publication Year :
- 2023
-
Abstract
- Rapid influenza diagnostic tests (RIDTs) have variable sensitivity. In a community‐based population of kindergarten through 12th‐grade (K‐12) students, we assessed factors that may influence RIDT performance using 2368 paired results from Sofia® influenza A + B fluorescent immunoassay and reverse transcription polymerase chain reaction (RT‐PCR). RIDT sensitivity and specificity were 76.1% (95% CI: 72.8–79.1) and 97.2% (96.2–97.9), respectively. Factors associated with sensitivity included runny nose (OR = 3.0, p < 0.001), nasal congestion (1.59, p = 0.045), days from symptom onset (per day; 0.75; p < 0.001), myalgia (0.61; p = 0.014), age (per 5 years; 0.55; p = 0.001), and detection of another virus (0.50; p = 0.043). Understanding these factors can aid in interpreting negative results. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17502640
- Volume :
- 17
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Influenza & Other Respiratory Viruses
- Publication Type :
- Academic Journal
- Accession number :
- 161547495
- Full Text :
- https://doi.org/10.1111/irv.13064