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What repeat expansion disorders can teach us about the Central Dogma.
- Source :
-
Molecular Cell . Feb2023, Vol. 83 Issue 3, p324-329. 6p. - Publication Year :
- 2023
-
Abstract
- Pathogenic repeat sequences underlie several human disorders, including amyotrophic lateral sclerosis, Huntington's disease, and myotonic dystrophy. Here, we speak to several researchers about how repeat sequences have been implicated in affecting all aspects of the Central Dogma of molecular biology through their effects on DNA, RNA, and protein. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10972765
- Volume :
- 83
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Molecular Cell
- Publication Type :
- Academic Journal
- Accession number :
- 161584153
- Full Text :
- https://doi.org/10.1016/j.molcel.2022.12.017