脱细胞异体真皮在上睑及内眦后层缺损重建中的 临床应用.

Objective To investigate the clinical application of acellular human dermis graft (Alloderm) for reconstruction of posterior upper eyelid and inner canthus defects. Methods From September 2020 to April 2021, 7 cases of patients with full-thickness upper eyelid and/or inner canthus defects, by using Alloderm as posterior lamella and pedicled flap as anterior lamella, were analyzed retrospectively. Four cases were upper eyelid defects, 1 case was inner canthus and upper eyelid defects, 2 cases were inner canthus and upper, lower eyelid defects. Follow-up was performed to evaluate complications and surgical results. Results All cases were followed-up for 6 to 12 months with good surface conjunctivization and stable tarsal support, without corneal irritation, symblepharon, entropion or ectropion. All patients had no conjunctival hyperemia, foreign body sensation and other symptoms. Eye movement was good. No symblepharon, entropion or eversion of the eyelids occurred. The effective repair rate was 85.7%. Four cases were cured, 1 case was markedly improved, and 1 case was improved. Conclusion Alloderm can avoid corneal injury and symblepharon. This method is a good substitute material for reconstruction of posterior upper eyelid and inner canthus defects. [ABSTRACT FROM AUTHOR]