Back to Search
Start Over
One-step fabrication of hydrophobic metal-organic framework@covalent organic framework hybrid as sorbent for high-performance solid-phase extraction of flavonoids.
- Source :
-
Journal of Chromatography A . Feb2023, Vol. 1691, pN.PAG-N.PAG. 1p. - Publication Year :
- 2023
-
Abstract
- • A hydrophobic NH 2 -UiO-66@H COF hybrid was successfully fabricated and explored as a promising SPE sorbent. • The NH 2 -UiO-66@H COF hybrid exhibited better extraction performance than NH 2 -UiO-66 and H COF via synergistic effects. • A sensitive detection method was established for analysis of flavonoids in food samples. Metal-organic framework (MOF) and covalent organic framework (COF) exhibit excellent extraction performance in sample pretreatment, but their wider application is hindered by some inherent drawbacks. Herein, we successfully synthesized a novel MOF@COF hybrid material with large specific surface area, good chemical stability and reusability, which is suitable as a solid phase extraction (SPE) sorbent for the efficient extraction of flavonoids. Importantly, due to the synergistic effect, the obtained MOF@COF hybrid material showing a higher extraction efficiency than individual MOF and COF. This is mainly due to the obtained MOF@COF hybrid material combines the high specific surface area of MOF and multiple interactions (hydrophobic interaction, hydrogen bonding and π-π stacking interaction) with flavonoids conferred by the COF structure. Then, a sensitive analytical method for flavonoids with ideal linear range (1–500 ng mL−1), low detection limit (0.15–0.41 ng mL−1) and good repeatability (2.64–6.20%) was developed under optimized conditions. In addition, the MOF@COF hybrid sorbent has better selectivity for hydrophobic targets containing multiple hydrogen bond acceptors/donors. Finally, the established method was applied to the determination of flavonoids in different food samples, and satisfactory recoveries (81.4–102.1%) were obtained, which initially confirmed its applicability. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00219673
- Volume :
- 1691
- Database :
- Academic Search Index
- Journal :
- Journal of Chromatography A
- Publication Type :
- Academic Journal
- Accession number :
- 161818416
- Full Text :
- https://doi.org/10.1016/j.chroma.2023.463814