Increased Cerebellum 18F‐DPA‐714 Uptake in Anti‐Glutamate Kainate Receptor Subunit 2 Autoimmune Encephalitis.

Brain magnetic resonance imaging (MRI) performed in 2022 showed abnormal signals in bilateral upper cerebellar hemisphere, cerebellar vermis, bilateral thalamus, and bilateral hippocampus (Fig. Increased Cerebellum 18F-DPA-714 Uptake in Anti-Glutamate Kainate Receptor Subunit 2 Autoimmune Encephalitis Anti-glutamate kainate receptor subunit 2 (Gluk2) autoimmune encephalitis (AE) is a novel and very rare neuroimmune disease that was first reported in 2021.[1] Eight patients with this rare form of AE have been reported globally.[1] Herein, we report a patient with anti-Gluk2 antibodies presenting as cerebellar dysfunctions and limbic encephalitis. [Extracted from the article]