Editorial of the Special Issue "Toxins: Mr Hyde or Dr Jekyll?".

Similar to most large toxins, the chemical synthesis of -bungarotoxin is challenging, explaining why all previous reports use purified or recombinant -bungarotoxin. , gave rise to three thematic sessions: the first on plant toxins, algal toxins and mycotoxins; the second on animal toxins; and the third on bacterial toxins. -Bungarotoxin is a large, 74 amino acid toxin containing five disulfide bridges, initially identified in the venom of I Bungarus multicinctus i snake. Gambierol is a polycyclic ether toxin produced by the dinoflagellate I Gambierdiscus toxicus i that is a potent neurotoxin by blocking voltage-gated potassium channels. [Extracted from the article]