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Mathematical analysis of Hepatitis C Virus infection model in the framework of non-local and non-singular kernel fractional derivative.

Authors :
Slimane, Ibrahim
Nazir, Ghazala
Nieto, Juan J.
Yaqoob, Faheem
Source :
International Journal of Biomathematics. Jan2023, Vol. 16 Issue 1, p1-20. 20p.
Publication Year :
2023

Abstract

In this paper, we study a mathematical model of Hepatitis C Virus (HCV) infection. We present a compartmental mathematical model involving healthy hepatocytes, infected hepatocytes, non-activated dendritic cells, activated dendritic cells and cytotoxic T lymphocytes. The derivative used is of non-local fractional order and with non-singular kernel. The existence and uniqueness of the system is proven and its stability is analyzed. Then, by applying the Laplace Adomian decomposition method for the fractional derivative, we present the semi-analytical solution of the model. Finally, some numerical simulations are performed for concrete values of the parameters and several graphs are plotted to reveal the qualitative properties of the solutions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17935245
Volume :
16
Issue :
1
Database :
Academic Search Index
Journal :
International Journal of Biomathematics
Publication Type :
Academic Journal
Accession number :
162295937
Full Text :
https://doi.org/10.1142/S1793524522500644