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Deep learning application detecting SARS-CoV-2 key enzymes inhibitors.

Authors :
Benarous, Leila
Benarous, Khedidja
Muhammad, Ghulam
Ali, Zulfiqar
Source :
Cluster Computing. Apr2023, Vol. 26 Issue 2, p1169-1180. 12p.
Publication Year :
2023

Abstract

The fast spread of the COVID-19 over the world pressured scientists to find its cures. Especially, with the disastrous results, it engendered from human life losses to long-term impacts on infected people's health and the huge financial losses. In addition to the massive efforts made by researchers and medicals on finding safe, smart, fast, and efficient methods to accurately make an early diagnosis of the COVID-19. Some researchers focused on finding drugs to treat the disease and its symptoms, others worked on creating effective vaccines, while several concentrated on finding inhibitors for the key enzymes of the virus, to reduce its spreading and reproduction inside the human body. These enzymes' inhibitors are usually found in aliments, plants, fungi, or even in some drugs. Since these inhibitors slow and halt the replication of the virus in the human body, they can help fight it at an early stage saving the patient from death risk. Moreover, if the human body's immune system gets rid of the virus at the early stage it can be spared from the disastrous sequels it may leave inside the patient's body. Our research aims to find aliments and plants that are rich in these inhibitors. In this paper, we developed a deep learning application that is trained with various aliments, plants, and drugs to detect if a component contains SARS-CoV-2 key inhibitor(s) intending to help them find more sources containing these inhibitors. The application is trained to identify various sources rich in thirteen coronavirus-2 key inhibitors. The sources are currently just aliments, plants, and seeds and the identification is done by their names. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13867857
Volume :
26
Issue :
2
Database :
Academic Search Index
Journal :
Cluster Computing
Publication Type :
Academic Journal
Accession number :
162508942
Full Text :
https://doi.org/10.1007/s10586-022-03656-6