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Correlated Evolution among Six Gene Families in Drosophila Revealed by Parallel Change of Gene Numbers.

Authors :
Dong-Dong Wu
Irwin, David M.
Ya-Ping Zhang
Source :
Genome Biology & Evolution. 2011, Vol. 3, p396-400. 5p. 3 Charts, 1 Graph.
Publication Year :
2011

Abstract

Proteins involved in a pathway are likely to evolve in a correlated fashion, and coevolving gene families tend to undergo complementary gains and losses. Accordingly, gene copy numbers (i.e., repertoire size) tend to show parallel changes during the evolution of coevolving gene families. To test and verify this hypothesis, here we describe positive correlations among the repertoire sizes of six gene families, that is, trypsin-like serine protease, odorant-binding protein, odorant receptor, gustatory receptor, cytochrome P450, and glutathione S-transferase after excluding the possibility of phylogenetic constraint and random drift. The observed correlations are indicative of parallel changes in the repertoire sizes of the six gene families that are due to similar demands for the quantity of these different genes in different lineages of Drosophila. In conclusion, we propose that the correlated evolution among these six gene families in Drosophila is a signature of a parallel response to ecological adaptation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17596653
Volume :
3
Database :
Academic Search Index
Journal :
Genome Biology & Evolution
Publication Type :
Academic Journal
Accession number :
162536410
Full Text :
https://doi.org/10.1093/gbe/evr034