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Clinical and Pathological Features of Congenital Hepatic Hemangioma in Children: A Retrospective Analysis.
- Source :
-
Fetal & Pediatric Pathology . Apr2023, Vol. 42 Issue 2, p198-206. 9p. - Publication Year :
- 2023
-
Abstract
- Objective: We reviewed our experience with congenital hepatic hemangiomas (CHH) to assess the effectiveness of our treatment strategies. Methods: Clinical and pathologic features of children with CHH were reviewed. Results: Twenty-two cases of CHH were collected, 17 were resected and 5 were followed until resolution. In 17 with alpha-feto-protein (AFP) levels, 9 were elevated with 5 decreasing to normal before surgery. In six with tumors under 3 cm, five regressed between 1 and 13 months, one required removal 5 years after initial diagnosis. Postoperative histopathology of 17 cases showed abnormal vascular hyperplasia without lobular architecture. CD34 was expressed in all tumors, glucose transporter 1(Glut1) was negative. Conclusion: If the tumor is less than 3 cm, AFP is normal and there are no obvious complications, the lesion can be followed with regular assessment imaging. Surgical resection is an option in tumors less than 3 cm which have not regressed over time. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15513815
- Volume :
- 42
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Fetal & Pediatric Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 162670605
- Full Text :
- https://doi.org/10.1080/15513815.2022.2114300