Trifluoromethylation of Carbonyl and Unactivated Olefin Derivatives by C(sp3)−C Bond Cleavage.

Herein, we report a Cu‐mediated trifluoromethylation of carbonyl‐type compounds and unactivated olefins enabled by visible‐light irradiation via σ C(sp3)−C bond‐functionalization. The reaction is distinguished by its modularity, mild conditions and wide scope—even in the context of late‐stage functionalization—thus offering a complementary approach en route to valuable C(sp3)−CF3 architectures from easily accessible precursors. [ABSTRACT FROM AUTHOR]