A Green Approach for the Synthesis of 1,4‐Diphenylbutadiyne‐1,3 via C−H Activated Aerobic Csp−Csp Homocoupling Catalyzed by CuFe2O4 Nanoparticles.

An inexpensive, simple, and greener catalytic system with lower toxicity using CuFe2O4 nanoparticles in the presence of piperidine and dry toluene as a solvent has been reported for the synthesis of 1,4‐diphenylbutadiyne‐1,3, via C−H activated aerobic Csp−Csp homocoupling. This protocol provides 66 % of yield at the gram‐scale level making it appropriate for production at a larger scale. The catalyst shows reusability for up to five cycles without losing any significant catalytic activity. [ABSTRACT FROM AUTHOR]