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Limited Clinical Value of Anti-Retinal Antibody Titers and Numbers in Autoimmune Retinopathy.
- Source :
-
Clinical Ophthalmology . Mar2023, Vol. 17, p749-755. 7p. - Publication Year :
- 2023
-
Abstract
- Purpose: To assess the possible correlation of anti-retinal antibody titers and number of anti-retinal antibodies with outcome measurements including visual acuity, subjective vision loss, visual field, and electroretinography in patients with autoimmune retinopathy. Design: Single-center, retrospective cross-sectional study. Patients and Methods: Patients with autoimmune retinopathy who underwent anti-retinal antibody testing at least twice during their follow-up were enrolled. Anti-retinal antibody titers and numbers were grouped as improved, stable, or worsened. Outcomes included Snellen visual acuity, patient-reported vision loss, Humphrey visual field mean deviations, and electroretinography parameters. Results: Thirty-one eyes among 16 patients with autoimmune retinopathy were included. Between-group analyses of visual acuity, subjective vision loss, visual field, and electroretinography outcomes did not reveal any significant differences by anti-retinal antibody titer or number group at a 95% confidence interval. Conclusion: Changes in anti-retinal antibody titers or numbers were not associated with any vision outcome. Repeated anti-retinal antibody testing may be unnecessary after diagnosis of autoimmune retinopathy and detection of an anti-retinal antibody. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 11775467
- Volume :
- 17
- Database :
- Academic Search Index
- Journal :
- Clinical Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 162857390
- Full Text :
- https://doi.org/10.2147/OPTH.S404826