The Last Fortress of Tin's Tyranny – Protodenitration of Nitroalkanes.

Protodenitration, a direct reduction of nitroalkanes to corresponding alkanes, already spans two centuries and is enabled by various reagents. This mini‐review provides a historical development of the fundamental transformation and highlights the governing position of the Ono‐Tanner reaction employing tributyltin hydride. Due to the unchallenged dominance of the toxic tributyltin hydride and environmentally unpopular solvents sharply contrasting with modern ecological trends, the current situation was dubbed "the last fortress of tin's tyranny." [ABSTRACT FROM AUTHOR]