Observational study at tertiary care hospital regarding clinical profile of lung cancer and its paraneoplastic manifestations.

Lung cancer is a common cause of mortality in Indian population amongst cancer causes. Risk factor identification and past medical comorbidities are predisposing factors for occurrence of carcinoma. Identification of other symptoms associated with endogenous hormone release could have positive outcome by early diagnosis of lung cancer. Method: This prospective observational study was conducted in 18-80 year patients of armed forces hospital who met the inclusion criteria. Clinical presentation, all risk factors were identified, paraneoplastic manifestations noted and managed. Results: Mean age was 61.5 years, 48 males and 12 females with associated risk factor of smoking intake identified. Cough (58%) and chest pain (18%) were main presenting symptoms. Cachexia, hypercalcemia, SIADH and superior mesenteric artery thrombosis were paraneoplastic manifestations noted. Conclusion: Delayed diagnosis due to nonspecific symptoms are responsible for worrisome outcome of lung cancer. Vigilant diagnosis of paraneoplastic manifestations can help in early diagnosis of primary carcinoma and better outcome. [ABSTRACT FROM AUTHOR]