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Granulocyte products: The saga continues.

Authors :
Klinkmann, Gerd
Goudeva, Lilia
Blasczyk, Rainer
Mitzner, Steffen
Altrichter, Jens
Source :
Transfusion. Apr2023, Vol. 63 Issue 4, p894-896. 3p.
Publication Year :
2023

Abstract

However, Schwanke et al. have already reported a decrease in phagocytosis and oxidative burst performance of standard GC of as much as 50% after 24 h and about 15% after 72 h of storage, underlining the tremendous functional improvement in purified GC after 72 h.[4] We completely agree with Baykara et al. that any new medical technology/treatment should finally be judged in practice. First of all, we are delighted about the interest of Baykara et al.'s group of authors on our novel purification procedure for granulocyte concentrates (GC).[1] So far, the therapeutic use of GC has been reserved for distinct indications. In particular, we were able to develop a method to use GC in an extracorporeal therapy system for the treatment of sepsis-induced immune paralysis. [Extracted from the article]

Subjects

Subjects :
*SEPTIC shock

Details

Language :
English
ISSN :
00411132
Volume :
63
Issue :
4
Database :
Academic Search Index
Journal :
Transfusion
Publication Type :
Academic Journal
Accession number :
163021398
Full Text :
https://doi.org/10.1111/trf.17291