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Near-infrared refractive detection of newly freshly-excised human-liver tissues: an optical refractive index biosensor based on 2D-photonic crystal.

Authors :
Basri, Rehana
Alam, Mohammad Khursheed
Ramanujam, N. R.
Sayeed, Mohammed Ubaidullah
Munisekhar, Manay Srinivas
Ganji, Kiran Kumar
Nagarajappa, Anil Kumar
Source :
Optical & Quantum Electronics. May2023, Vol. 55 Issue 5, p1-14. 14p.
Publication Year :
2023

Abstract

In this paper, we report on the detection and measurement of refractive properties of healthy and cancerous human liver samples taken from real data using a prism pair technique that covers the near-visible and infrared spectral range. Then, according to real samples, an all-optical refractive index biosensor is designed and simulated. Newly used data on the wavelength-dependent refractive index of human liver tissues are presented and detected under different conditions. Remarkably, the real index contrast is mentioned as an index of the difference between normal liver tissue and liver metastases. According to real data from the human body, a special account can be made on the detection of the healthy and cancerous liver in this article. Numerous photon crystal-based biosensors are proposed for various diseases, but no serious research has been done on unhealthy livers, and this article tries to cover this type of disease as well. The obtained sensitivity values are reported as 1000 nm/RIU for the given bio samples. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03068919
Volume :
55
Issue :
5
Database :
Academic Search Index
Journal :
Optical & Quantum Electronics
Publication Type :
Academic Journal
Accession number :
163122286
Full Text :
https://doi.org/10.1007/s11082-023-04697-w