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Outcomes of patients with therapy‐related myeloid neoplasms after treatment with poly(ADP‐ribose) polymerase proteins inhibitors for solid tumours.

Authors :
Almanza‐Huante, Emmanuel
Bataller, Alex
Urrutia, Samuel
Gener‐Ricos, Georgina
Briski, Robert Edward
Kanagal‐Shamanna, Rashmi
Lu, Karen H.
Westin, Shannon N.
Yap, Timothy A.
Takahashi, Koichi
Ravandi, Farhad
Alvarado, Yesid
Kadia, Tapan
Sasaki, Koiji
Kantarjian, Hagop M.
Garcia‐Manero, Guillermo
Source :
British Journal of Haematology. May2023, Vol. 201 Issue 3, pe25-e29. 5p.
Publication Year :
2023

Abstract

Therapy-related myeloid neoplasms following treatment with PARP inhibitors: new molecular insights. Keywords: PARP inhibitors; therapy related myeloid neoplasms; therapy-related acute myeloid leukaemia; therapy-related myelodysplastic syndrome EN PARP inhibitors therapy related myeloid neoplasms therapy-related acute myeloid leukaemia therapy-related myelodysplastic syndrome e25 e29 5 04/20/23 20230501 NES 230501 Therapy-related myeloid neoplasms represent 10%-20% of all newly diagnosed myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML).[1] These disorders are frequently associated with high-risk genetic features. Outcomes of patients with therapy-related myeloid neoplasms after treatment with poly(ADP-ribose) polymerase proteins inhibitors for solid tumours Therapy related myeloid neoplasms, PARP inhibitors, therapy-related myelodysplastic syndrome, therapy-related acute myeloid leukaemia. [Extracted from the article]

Details

Language :
English
ISSN :
00071048
Volume :
201
Issue :
3
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
163161020
Full Text :
https://doi.org/10.1111/bjh.18766