Direct oral anticoagulants should often be suspended for longer before neuraxial blockade.

There is a little of information concerning which plasma concentrations of DOACs are safe when administering central neuraxial blocks (CNBs) and there is a wide variability in the rate of elimination, both between individuals and DOACs. Keywords: direct acting oral coagulants; DOAC; hemorrhage; neuraxial block; risk; surgery EN direct acting oral coagulants DOAC hemorrhage neuraxial block risk surgery 682 683 2 04/24/23 20230501 NES 230501 Direct oral anticoagulants (DOACs) require perioperative vigilance to reduce the risk of spinal hematoma. DOAC, direct acting oral coagulants, hemorrhage, neuraxial block, risk, surgery. [Extracted from the article]