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Preliminary study on the effect of ozone exposure on blood glucose level in rats.
- Source :
-
Technology & Health Care . 2023SupplemenS1, Vol. 31, p303-311. 9p. - Publication Year :
- 2023
-
Abstract
- BACKGROUND: In recent years, people have paid more and more attention to the health hazards caused by O 3 exposure, which will become a major problem after fine particulate matter (PM). OBJECTIVE: To investigate the effects of ozone (O 3) exposure on blood glucose levels in rats under different concentrations and times. METHODS: Eighty rats were divided into control group and three ozone concentration groups. Each group was continuously exposed for 1d, 3d and, 6d, and exposed for 6 hours daily. After exposure, GTT, FBG, and random blood glucose were measured. RESULTS: The FBG value increased significantly on the 6th day of 0.5 ppm and the 3rd and 6th days of 1.0 ppm exposure compared with the control group (P < 0.05). The random blood glucose value was significantly increased on the 3rd and 6th days of each exposure concentration (P < 0.05). When exposed to 1 ppm concentration, the 120 min GTT value of 1 d, 3 d and, 6 d was significantly higher than that of the control group (P < 0.05). CONCLUSION: After acute O 3 exposure, the blood glucose level of rats was affected by the exposure concentration and time. The concentration of 0.1 ppm had no significant impact on FBG and random blood glucose, and O 3 with a concentration of 0.1 ppm and 0.5 ppm had no significant impact on values of GTT at 90 min, and 120 min. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OZONE
*GLUCOSE tolerance tests
*PARTICULATE matter
*RATS
Subjects
Details
- Language :
- English
- ISSN :
- 09287329
- Volume :
- 31
- Database :
- Academic Search Index
- Journal :
- Technology & Health Care
- Publication Type :
- Academic Journal
- Accession number :
- 163483367
- Full Text :
- https://doi.org/10.3233/THC-236026