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Comparative efficacy of psychosocial interventions for opioid‐dependent people receiving methadone maintenance treatment: A network meta‐analysis.
- Source :
-
Addiction . Jun2023, Vol. 118 Issue 6, p1029-1039. 11p. 2 Diagrams, 4 Charts, 1 Graph. - Publication Year :
- 2023
-
Abstract
- Aims: To estimate the efficacy of multiple psychosocial interventions for opioid‐dependent people receiving methadone maintenance treatment (MMT). Methods: Systematic review and network meta‐analysis of randomized controlled trials (RCTs) reporting the effect of psychosocial intervention for opioid‐dependent people receiving MMT in outpatient clinics. We searched multiple data sources (Medline, Embase, Web of Science, PsycINFO and Cochrane Library) from inception to January 2022, finding 21 RCTs evaluating a total of 2862 people with opioid dependence receiving MMT. The primary outcome was the opioid‐positive rate (assessed by urinalysis) and the secondary outcome was treatment discontinuation (the number of patients who terminated the study for any reason). We performed random‐effects Bayesian meta‐analysis. We used relative ranking using surface under the cumulative ranking method and certainty of evidence using grading of recommendations, assessment, development and evaluations. Results: Cognitive–behavioral therapy (CBT) [odds ratio (OR) = 0.66, 95% credible interval (CI) = 0.66–0.96; low certainty] and educational and behavioral counseling (EBC) (OR = 0.28, 95% CI = 0.12–0.25; high certainty) were more effective than treatment as usual (TAU) in efficacy. In terms of treatment discontinuation, at the end of the follow‐up period there was no statistical significance among psychosocial interventions. According to the ranking probabilities, EBC might be the most effective treatment and behavioral couples' therapy (BCT) might be the best discontinuation treatment. Conclusions: Educational and behavioral counseling and cognitive–behavioral therapy appear to be the most effective psychosocial interventions for opioid‐dependent people receiving methadone maintenance treatment. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SUBSTANCE abuse treatment
*METHADONE treatment programs
*PSYCHOLOGY information storage & retrieval systems
*MEDICAL databases
*META-analysis
*MEDICAL information storage & retrieval systems
*SUBSTANCE abuse
*COUNSELING
*SYSTEMATIC reviews
*COGNITION
*TREATMENT effectiveness
*RESEARCH funding
*DESCRIPTIVE statistics
*MEDLINE
*URINALYSIS
*ODDS ratio
*TERMINATION of treatment
*PSYCHOTHERAPY
*OUTPATIENT services in hospitals
*COGNITIVE therapy
Subjects
Details
- Language :
- English
- ISSN :
- 09652140
- Volume :
- 118
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Addiction
- Publication Type :
- Academic Journal
- Accession number :
- 163589561
- Full Text :
- https://doi.org/10.1111/add.16167