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Divergent Functionalization of Alkynes Enabled by Organic Photoredox Catalysis.
- Source :
-
Synlett . Jun2023, Vol. 34 Issue 9, p1023-1028. 6p. - Publication Year :
- 2023
-
Abstract
- Direct functionalization of alkynes under oxidative conditions is challenging, as alkynes are usually recalcitrant towards typical oxidants. Herein, we communicate a strategy for the divergent functionalization of alkynes with photoexcited acridinium organic dyes, presumably via the formation of vinyl cation radicals as key intermediates. Based on the nature of the nucleophiles, different types of difunctionalized products were obtained in moderate to good yields. Addition of lithium Lewis acids resulted in a surprising reversal of diastereocontrol. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ALKYNES
*CATALYSIS
*RADICAL cations
*LEWIS acids
*ORGANIC dyes
Subjects
Details
- Language :
- English
- ISSN :
- 09365214
- Volume :
- 34
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Synlett
- Publication Type :
- Academic Journal
- Accession number :
- 163655619
- Full Text :
- https://doi.org/10.1055/a-2009-8279