Back to Search
Start Over
Radical bicyclization of 1,6-enynes with sulfonyl hydrazides by the use of TBAI/TBHP in the aqueous phase.
- Source :
-
Chemical Communications . 5/25/2023, Vol. 59 Issue 42, p6391-6394. 4p. - Publication Year :
- 2023
-
Abstract
- A novel 5-exo-dig/6-endo-trig bicyclization of 1,6-enynes with sulfonyl hydrazides in the aqueous phase using the cheap and available tetrabutylammonium iodide (TBAI)–tert-butyl hydroperoxide (TBHP) combined system is reported. The resulting reaction of diverse nitrogen- and oxygen-polyheterocycles displays high chemical selectivity, high step-economy, and a moderate substrate scope. Moreover, iodosulfonylation can be realized by modulating the structure of the 1,6-enynes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDRAZIDES
*SULFONYL compounds
*IODIDES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 59
- Issue :
- 42
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 163874681
- Full Text :
- https://doi.org/10.1039/d3cc01102j