Synthesis and Antifungal Activity of Indole Derivatives.

A total of 20 new indole analogs were synthesized and evaluated for biological activity against Sclerotinia sclerotiorum, Altenaria solani, Verticillium dahliae, Fusarium oxysporum, Pythium walnuts, and Curvularia zea. The preliminary biological testing showed that most of the synthesized compounds exhibited fungicidal activities. Notably, compounds 2 and 7 showed the broadest and most effective activities among the compounds tested and could be potential new lead compounds for the future development of antifungal agents. [ABSTRACT FROM AUTHOR]