Back to Search Start Over

The importance of frailty assessment in multiple myeloma: a position statement from the Myeloma Scientific Advisory Group to Myeloma Australia.

Authors :
Sim, Shirlene
Kalff, Anna
Tuch, Gina
Mollee, Peter
Ho, P. Joy
Harrison, Simon
Gibbs, Simon
Prince, H. Miles
Spencer, Andrew
Joshua, Douglas
Lee, Cindy
Ling, Silvia
Murphy, Nick
Szabo, Ferenc
Szer, Jeff
Weber, Nicholas
Ward, Christopher
Talaulikar, Dipti
Zannettino, Andrew
Quach, Hang
Source :
Internal Medicine Journal. May2023, Vol. 53 Issue 5, p819-824. 6p.
Publication Year :
2023

Abstract

Multiple myeloma (MM) is a disease of older people, yet factors relating to comorbidity and frailty may threaten treatment tolerability for many of this heterogenous group. There has been increasing interest in defining specific and clinically relevant frailty assessment tools within the MM population, with the goal of using these frailty scores, not just as a prognostic instrument, but also as a predictive tool to allow for a frailty‐adapted treatment approach. This paper reviews the various frailty assessment frameworks used in the evaluation of patients with MM, including the International Myeloma Working Group Frailty Index (IMWG‐FI), the Mayo Frailty Index and the simplified frailty scale. While the IMWG‐FI remains the most widely accepted tool, the simplified frailty scale is the most user‐friendly in busy day‐to‐day clinics based on its ease of use. This paper summarises the recommendations from the Myeloma Scientific Advisory Group (MSAG) of Myeloma Australia, on the use of frailty assessment tools in clinical practice and proposes a frailty‐stratified treatment algorithm to aid clinicians in tailoring therapy for this highly heterogeneous patient population. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14440903
Volume :
53
Issue :
5
Database :
Academic Search Index
Journal :
Internal Medicine Journal
Publication Type :
Academic Journal
Accession number :
163887949
Full Text :
https://doi.org/10.1111/imj.16049