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Histological analysis of different types of port-wine stains to guide clinical decision making: A retrospective study.
- Source :
-
Indian Journal of Dermatology, Venereology & Leprology . Mar/Apr2023, Vol. 89 Issue 2, p204-212. 9p. - Publication Year :
- 2023
-
Abstract
- Background and objectives: Port-wine stains are defined as congenital benign vascular lesions. The treatment of port-wine stains remains a challenge, worldwide. This study aimed to analyze the histological characteristics in different types of port-wine stains and provide guidance for clinical decision-making. Methods and materials: Biopsies were from the hospital from 2015 to 2021. H&E staining, Immunofluorescence staining, Masson's trichrome staining and Weigert staining were performed on the tissues. Results: A total of 35 port-wine stains patients were included in the study of four distinct types, namely red port-wine stains (11 cases), purple port-wine stains (seven cases), hypertrophic port-wine stains (nine cases) and nodular port-wine stains (eight cases). The mean vessel diameter of the different types was 38.7 ± 5.9 µm, 93.5 ± 9.7 µm, 155.6 ± 21.8 µm and 155.6 ± 29.54 µm, respectively. Mean vessel depth was 396.4 ± 31 µm, 944.2 ± 105.4 µm, 2,971 ± 161.3 µm and 3,594 ± 364.6 µm, respectively. The vessels in red port-wine stains, purple port-wine stains and hypertrophic port-wine stains were mainly composed of capillary and venous malformations, whereas those in nodular port-wine stains were venous or arteriovenous malformations. Limitation: The main limitation of the current study was the small number of patients. Conclusion: As the disease progresses, vessel diameters become larger, the vessel wall becomes thicker and vessels were found in a greater depth. A treatment plan should be scientifically formulated keeping in mind the histological characteristics of port-wine stains. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STAINS & staining (Microscopy)
*DECISION making
*HEMATOXYLIN & eosin staining
Subjects
Details
- Language :
- English
- ISSN :
- 03786323
- Volume :
- 89
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Dermatology, Venereology & Leprology
- Publication Type :
- Academic Journal
- Accession number :
- 164028701
- Full Text :
- https://doi.org/10.25259/IJDVL_730_2021