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Catalyst‐Free Defluoroalkylation of Trifluoromethylated Alkenes via Photoinduced Electron Donor‐Acceptor Complex.
- Source :
-
ChemistrySelect . 6/13/2023, Vol. 8 Issue 22, p1-5. 5p. - Publication Year :
- 2023
-
Abstract
- Radicals can be formed expeditiously through the direct irradiation of an electron donor‐acceptor (EDA) complex. Herein, we show a photocatalyst‐free strategy for gem‐difluoroalkenes synthesis realized by photo‐irradiation of the EDA complexes, which can be generated in situ between N‐alkylpyridinium salts and Hantzsch ester without any other additives. A wide variety of readily available alkylamines underwent deaminative defluoroalkylation to provide the corresponding gem‐difluoroalkenes. This reaction system exhibits high reactivity and good functional group tolerance and provides a practical and effective entry to a broad range of α‐alkyl‐substituted gem‐difluoroalkenes. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23656549
- Volume :
- 8
- Issue :
- 22
- Database :
- Academic Search Index
- Journal :
- ChemistrySelect
- Publication Type :
- Academic Journal
- Accession number :
- 164306815
- Full Text :
- https://doi.org/10.1002/slct.202300665