Establishment and Evaluation of Intelligent Diagnostic Model for Ophthalmic Ultrasound Images Based on Deep Learning.

The goal of the work described here was to construct a deep learning–based intelligent diagnostic model for ophthalmic ultrasound images to provide auxiliary analysis for the intelligent clinical diagnosis of posterior ocular segment diseases. The InceptionV3–Xception fusion model was established by using two pre-trained network models—InceptionV3 and Xception—in series to achieve multilevel feature extraction and fusion, and a classifier more suitable for the multiclassification recognition task of ophthalmic ultrasound images was designed to classify 3402 ophthalmic ultrasound images. The accuracy, macro-average precision, macro-average sensitivity, macro-average F1 value, subject working feature curves and area under the curve were used as model evaluation metrics, and the credibility of the model was assessed by testing the decision basis of the model using a gradient-weighted class activation mapping method. The accuracy, precision, sensitivity and area under the subject working feature curve of the InceptionV3–Xception fusion model on the test set reached 0.9673, 0.9521, 0.9528 and 0.9988, respectively. The model decision basis was consistent with the clinical diagnosis basis of the ophthalmologist, which proves that the model has good reliability. The deep learning–based ophthalmic ultrasound image intelligent diagnosis model can accurately screen and identify five posterior ocular segment diseases, which is beneficial to the intelligent development of ophthalmic clinical diagnosis. [ABSTRACT FROM AUTHOR]