血管内介入治疗颅内动脉瘤合并缺血性脑血管疾病的临床研究.

Objective: To investigate the safety and effectiveness of endovascular intervention in the treatment of intracranial aneurysm (IA) complicated with ischemic cerebrovascular disease. Methods: The clinical data of 32 patients with IA complicated with ischemic cerebrovascular disease treated by endovascular intervention from January 2018 to December 2020 were retrospectively analyzed. Results: A total of 35 IA and 37 stenoses were found in 32 patients. The average size of IA was (5.17.3.12)mm Among them, 26 aneurysms (74%) were located in the internal carotid artery, 9 aneurysms (26%) were located in the vertebrobasilar artery, and 7 patients (22%) were found to have two intracranial aneurysms before operation. Among 37 stenosis, 9 (24%) were located in the vertebrobasilar artery, 8 (22%) were located in the extracranial segment, and the remaining 20 (54%) were located in the internal carotid artery. The average stenosis rate was 75.7% before operation. 31 aneurysms (89%) were completely occluded and 4 aneurysms (11%) remained in the neck. Among 37 stenoses, the average stenosis rate after operation was 8.8%, and the distal cerebral vessels of all patients were unobstructed after operation. During the treatment, there was 1 case of in-stent restenosis and 1 case of cerebral vasospasm. The modified Rankin scale (mRS) was less than 2 in all patients at discharge. All the 32 patients were followed up by digital subtract angiography (DSA) for 6 to 18 months (average 8.8 months). During the follow-up, 1 case had in-stent restenosis. Conclusions: Endovascular intervention is safe and effective in the treatment of IA complicated with ischemic cerebrovascular diseases, which is worthy of clinical reference. [ABSTRACT FROM AUTHOR]