Effects of X-rays on some immunological parameters and FOXP3 expression level in radiological employees.

The main aim of the present investigation is to estimate the risks of ionization radiation exposure. This is performed by assessing the relationship between the intensities of ionization radiation exposure and the level of expression of the forkhead box P3 (FOXP3), which is expected to amplitude the fundamental hazards that radiological employees are subjected to. The current investigation was initiated in August and finished in December 2019. The study matrix consists of 60 contributors. These contributors were categorized into two main groups: radiographers (30 contributors) and healthy members as a control group (30 contributors). A complete blood picture analysis, FOXP3 level, and ESR were acquired by obtaining blood samples for all contributors. The dose equivalents of personal radiation were determined for all radiographers. The results of FOXP3 expression level for radiographers (p<0.0001) were remarkably higher than those obtained for the healthy contributors. In addition, it was noticed that the FOXP3 expression was positively related to personal radiation dose. The study showed that there is still a significant radiation risk even under well-prepared radiation protection. [ABSTRACT FROM AUTHOR]