Continuous-Flow Synthesis, Characterization, Antimicrobial Activity, and Docking Studies of Urea Derivatives of 4-(4-Aminophenyl)-3-morpholinone.

An efficient method was developed for the one-pot synthesis of novel series of urea derivatives from 4-(4-aminophenyl)-3-morpholinone via in situ generated isocyanate through continuous-flow system. All the compounds were docked against DNA gyrase enzyme and antimicrobial and antifungal activities were investigated. [ABSTRACT FROM AUTHOR]