代谢性脑血管病：概念、方法、挑战 和未来方向.

Metabolic risk factors are important causes of cardiovascular and cerebrovascular diseases. There is already a definite concept and comprehensive management system for cardio-metabolic disease. While the incidence rate of stroke is higher and exhibit greater heterogeneity in China, and lacks a concept of cerebro-metabolic disease currently. Therefore, we reviewed the metabolic risk factors of stroke, proposed the concept and classification of cerebro-metabolic disease, elucidated the interdisciplinary and multi-organ level research methods based on multi-omics technology, introduced the characteristics of recently emerged metabolic drugs with cardiovascular benefits and the challenges and future directions. We aimed to provide a theoretical basis for the comprehensive management of cerebro-metabolic disease. [ABSTRACT FROM AUTHOR]