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Proteínas oxidadas de origen animal y su impacto sobre la salud intestinal.

Authors :
Muñoz Verbe, Diemer
Cueto Almeida, Eutimio
Morales Meléndez, Valentina
Lombana, Amalfy García
Marenco, Dilia Aparicio
Márquez Lázaro, Johana
Source :
Medicina UPB. ene-jun2023, Vol. 42 Issue 1, p49-56. 8p.
Publication Year :
2023

Abstract

Animal foods such as chicken, beef, fish and pork are in wide demand throughout the world due, among other things, to their nutritional value, associated with their high protein content. However, this type of protein is susceptible to oxidation reactions, which can mediate processes of fragmentation, aggregation, loss of solubility, functionality, and protein digestibility, which are events involved in the loss of their nutritional value. In this sense, aggregated proteins tend not to be digested in the gastrointestinal tract and accumulate in the intestine (colon), where the colonic microbiota degrades them into mutagenic products such as phenol and p-cresol, which increases the risk of colorectal cancer. On the other hand, the oxidized amino acids or peptides released in digestion could be incorporated into intestinal cell signaling pathways and favor or exacerbate chronic intestinal processes such as irritable bowel syndrome or Crohn's disease. Due to the great interest in this topic in recent years, the objective of this review is to provide a general overview of the impact of oxidized proteins of animal origin on intestinal health. [ABSTRACT FROM AUTHOR]

Details

Language :
Spanish
ISSN :
01204874
Volume :
42
Issue :
1
Database :
Academic Search Index
Journal :
Medicina UPB
Publication Type :
Academic Journal
Accession number :
164812966
Full Text :
https://doi.org/10.18566/medupb.v42n1.a07