Serum MOG IgG titres should be performed routinely in the diagnosis and follow-up of MOGAD: Yes.

Interestingly, no patient in our cohort suffered from a relapse after time of first seroconversion, although fluctuating MOG-IgG titres with increase after a period of low or even negative MOG-IgG titres were reported in selected patients. Likewise, onset serum MOG-IgG titres, despite being important for the diagnosis of MOGAD, do not predict recovery or relapse.[1],[7] In most patients MOG-IgG titres decline with time, but may also remain positive in other patients for years. [Extracted from the article]